Description

2,4,6-Trichloro-3-Nitropyridine is a halogenated and nitrated heterocyclic building block of significant synthetic utility. This compound matters as a versatile intermediate for constructing complex molecules, particularly in the synthesis of advanced agrochemicals and active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development teams in the fine chemical, pharmaceutical, and agrochemical industries for creating novel compounds with targeted biological activity.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups for further functionalization.
• Pharmaceutical Building Block: Used in medicinal chemistry for the construction of complex heterocyclic scaffolds found in potential drug candidates, especially those targeting various enzymes and receptors.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, ligands, and organic electronic materials.
• Dye and Pigment Synthesis: Acts as an intermediate for producing specialized azo dyes and other colorants requiring stable, substituted pyridine cores.
• Cross-Coupling Reactions: The chlorine atoms provide excellent handles for palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce diverse aryl and alkyl groups.
• Nucleophilic Aromatic Substitution: The electron-deficient ring is highly amenable to substitution reactions with various nucleophiles, enabling rapid diversification.

Basic Information

Product Name	2,4,6-Trichloro-3-Nitropyridine
CAS No.	60186-13-2
Molecular Formula	C5HCl3N2O2
Molecular Weight	227.43 g/mol
Synonyms	3-Nitro-2,4,6-trichloropyridine; 2,4,6-Trichloro-3-nitropyridine; Pyridine, 2,4,6-trichloro-3-nitro-; 2,4,6-Trichloro-3-nitro-pyridine; NSC 406106; 3-Nitro-2,4,6-trichloropyridine; Trichloronitropyridine
EINECS	Contact for details

Quality Control

Our 2,4,6-Trichloro-3-Nitropyridine is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.