Description

(1R,4S)-cis-4-Acetoxy-2-Cyclopenten-1-Ol CAS NO 60176-77-4 is a high-purity chiral cyclopentenol derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its defined stereochemistry and functional group array make it a valuable building block for constructing complex molecules with precise three-dimensional architecture. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of prostaglandins, nucleoside analogs, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of prostaglandins and their analogs.
• Nucleoside Chemistry: Used in the preparation of modified nucleosides and nucleotides for antiviral and anticancer research.
• Asymmetric Synthesis: Serves as a versatile starting material or chiral auxiliary in catalytic asymmetric reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Item	Information
Product Name	(1R,4S)-cis-4-Acetoxy-2-Cyclopenten-1-Ol
CAS No.	60176-77-4
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	(1R,4S)-4-(Acetyloxy)-2-cyclopenten-1-ol; (1R,4S)-4-Acetoxy-2-cyclopenten-1-ol; cis-4-Acetoxy-2-cyclopenten-1-ol; 4-Acetoxy-2-cyclopenten-1-ol, (1R,4S)-rel-; (-)-cis-4-Acetoxy-2-cyclopenten-1-ol; 2-Cyclopenten-1-ol, 4-(acetyloxy)-, (1R,4S)-; Corey Lactone Acetate Intermediate
EINECS	Contact for details

Quality Control

Our (1R,4S)-cis-4-Acetoxy-2-Cyclopenten-1-Ol is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.