Description

5-Iodo-1-Methylpyridin-2(1H)-One is a versatile halogenated heterocyclic building block, specifically a pyridinone derivative, essential for advanced organic synthesis. Its core value lies in its unique reactivity, where the iodine atom serves as an excellent site for cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its halogenated structure allows for further functionalization.
• Material Science Research: Serves as a building block for creating specialized organic ligands, polymers, and advanced functional materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings to form new carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological systems and mechanisms.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic compounds.

Basic Information

Product Name	5-Iodo-1-Methylpyridin-2(1H)-One
CAS No.	60154-05-4
Molecular Formula	C6H6INO
Molecular Weight	235.03 g/mol
Synonyms	5-Iodo-1-methyl-2(1H)-pyridinone; 5-Iodo-1-methylpyridin-2-one; 1-Methyl-5-iodopyridin-2(1H)-one; 5-Iodo-1-methyl-2-pyridone; 2-Hydroxy-5-iodo-1-methylpyridinium; 5-Iodo-1-methyl-1,2-dihydropyridin-2-one
EINECS	Contact for details

Quality Control

Our 5-Iodo-1-Methylpyridin-2(1H)-One is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.