Description

Methyl 2-Bromo-2-(4-Bromophenyl)Acetate is a high-purity, versatile brominated aromatic ester that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its dual bromine functionality, which provides reactive handles for cross-coupling reactions and further molecular elaboration. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct complex molecules for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging its aromatic backbone for bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of monomers and functionalized polymers for advanced materials with specific optical or electronic properties.
• Organic Synthesis & Chemical Research: A versatile reagent for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and development candidates.

Basic Information

Product Name	Methyl 2-Bromo-2-(4-Bromophenyl)Acetate
CAS No.	60079-77-8
Molecular Formula	C9H8Br2O2
Molecular Weight	307.97 g/mol
Synonyms	Methyl α,4-Dibromobenzeneacetate; 2-Bromo-2-(4-bromophenyl)acetic acid methyl ester; Methyl (4-bromophenyl)bromoacetate; α,4-Dibromobenzeneacetic acid methyl ester; Methyl 2-bromo-2-(p-bromophenyl)acetate; p-Bromobenzyl bromoacetate (methyl ester); (4-Bromophenyl)(bromo)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Bromo-2-(4-Bromophenyl)Acetate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality commitment supports compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.