Description

L-Aspartic Acid, n-[(Phenylmethoxy)Carbonyl]-, 1-(1,1-Dimethylethyl) 4-Methyl Ester is a protected aspartic acid derivative, a crucial building block in organic synthesis. This compound is valued for its role in the controlled synthesis of peptides and other complex molecules, where protecting groups are essential for directing reactivity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemicals. The CAS number for this product is 60079-12-1.

Application

This protected amino acid derivative serves as a key intermediate in sophisticated synthetic pathways. Its primary applications include:

• Peptide Synthesis: As a critical building block for introducing aspartic acid residues in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: In the research and development of active pharmaceutical ingredients (APIs), particularly for peptide-based drugs.
• Bioconjugation Chemistry: For the site-specific modification of proteins, antibodies, or other biomolecules.
• Organic Synthesis Research: As a starting material or intermediate for synthesizing complex organic molecules and novel chemical entities in academic and industrial R&D.
• Protecting Group Strategy: Used in multi-step syntheses where the tert-butyl and benzyloxycarbonyl (Cbz) groups provide orthogonal protection for carboxylic acid and amine functionalities.

Basic Information

Product Name	L-Aspartic Acid, n-[(Phenylmethoxy)Carbonyl]-, 1-(1,1-Dimethylethyl) 4-Methyl Ester
CAS No.	60079-12-1
Molecular Formula	C16H21NO6
Molecular Weight	323.34 g/mol
Synonyms	N-Cbz-L-aspartic acid 4-methyl 1-tert-butyl ester; N-Carbobenzoxy-L-aspartic acid β-methyl α-tert-butyl ester; (2S)-4-Methoxy-2-[[(phenylmethoxy)carbonyl]amino]-4-oxobutanoic acid 1,1-dimethylethyl ester; L-Aspartic acid, N-(benzyloxycarbonyl)-, 1-tert-butyl 4-methyl ester; Cbz-Asp(OtBu)-OMe; Z-Asp(OtBu)-OMe; Nα-Cbz-L-aspartic acid 1-tert-butyl 4-methyl ester; Benzyl N-[(1S)-3-methoxy-1-[(2-methylpropan-2-yl)oxy]-1,3-dioxopropan-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development applications, with quality verified by analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) are available upon request, detailing purity and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.