Description

2-(Methoxyimino)Pentanedioic Acid Bis(Trimethylsilyl) Ester CAS NO 60022-87-9 is a specialized silylated derivative of glutamic acid, serving as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in enabling complex multi-step reactions, particularly in peptide and heterocyclic chemistry, by providing selective reactivity and enhanced solubility in non-polar media. This high-purity building block is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries who require precise molecular control.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and complex peptide analogs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and plant growth regulators.
• Peptide Chemistry: Acts as a protected glutamic acid derivative for solid-phase and solution-phase peptide synthesis.
• Material Science Research: Employed in the development of specialty polymers and functional organic materials.
• Chemical Biology Probes: Useful in the creation of labeled compounds and molecular probes for biochemical studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	2-(Methoxyimino)Pentanedioic Acid Bis(Trimethylsilyl) Ester
CAS No.	60022-87-9
Molecular Formula	C14H29NO5Si2
Molecular Weight	347.55 g/mol
Synonyms	Glutamic Acid, N-(Methoxyimino)-, Bis(trimethylsilyl) Ester; Bis(trimethylsilyl) 2-(Methoxyimino)pentanedioate; 2-(Methoxyimino)glutaric Acid Bis(trimethylsilyl) Ester; O-Methyloxime Derivative of Glutamic Acid Bis-TMS Ester; N-Methoxyglutamine Bis(trimethylsilyl) Ester; (TMS)2-Glu(OMe)Ox; 60022-87-9; Pentanedioic acid, 2-(methoxyimino)-, 1,5-bis(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our 2-(Methoxyimino)Pentanedioic Acid Bis(Trimethylsilyl) Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR, and IR for structural confirmation, and Karl Fischer titration for moisture content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.