Description

2-Chloro-6-Ethyl-Isonicotinamide is a specialized pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated and amide-substituted structure enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides due to its bioactive pyridine core.
• Fine Chemical Production: Serves as a versatile building block for synthesizing complex organic molecules in custom manufacturing.
• Research & Development: Essential for academic and industrial R&D labs exploring new chemical entities and reaction pathways.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	2-Chloro-6-Ethyl-Isonicotinamide
CAS No.	60019-49-0
Molecular Formula	C8H9ClN2O
Molecular Weight	184.62 g/mol
Synonyms	2-Chloro-6-ethylpyridine-4-carboxamide; 4-Pyridinecarboxamide, 2-chloro-6-ethyl-; 6-Ethyl-2-chloroisonicotinamide; Isonicotinamide, 2-chloro-6-ethyl-; 2-Chloro-6-ethyl-4-carbamoylpyridine; 2-Chloro-6-ethyl-4-pyridinecarboxamide; 2-Chloro-6-ethylisonicotinic acid amide
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Ethyl-Isonicotinamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.