Description

2,2-Difluoro-2-(Pyridin-3-Yl)Ethanamine is a valuable fluorinated pyridine derivative, serving as a key building block in advanced organic synthesis. Its unique structure, featuring both a difluoroethylamine moiety and a pyridine ring, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand Synthesis: Serves as a starting material for constructing complex ligands used in catalysis and material science.
• Fluorinated Building Block: Employed in medicinal chemistry for lead optimization, where introducing fluorine can improve metabolic stability, bioavailability, and binding affinity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	2,2-Difluoro-2-(Pyridin-3-Yl)Ethanamine
CAS No.	60010-40-4
Molecular Formula	C7H8F2N2
Molecular Weight	158.15 g/mol
Synonyms	3-(2,2-Difluoro-2-aminoethyl)pyridine; 2,2-Difluoro-2-(3-pyridyl)ethanamine; 2-Amino-1,1-difluoro-1-(3-pyridinyl)ethane; 1-(3-Pyridinyl)-2,2-difluoroethanamine; 3-(2-Amino-1,1-difluoroethyl)pyridine; 2,2-Difluoro-2-(pyridin-3-yl)ethan-1-amine
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-2-(Pyridin-3-Yl)Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.