Description

1,2-Dithiolane-3-Pentanoic Acid 1-Oxide is a specialized organosulfur compound of significant interest in biochemical and pharmaceutical research. This molecule, also known as α-lipoic acid sulfoxide, serves as a key intermediate and a biologically active derivative of the essential cofactor α-lipoic acid. It is primarily sought after by research institutions and manufacturers in the nutraceutical, pharmaceutical, and fine chemical synthesis sectors for its role in studying metabolic pathways and developing advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of α-lipoic acid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies of antioxidant mechanisms, mitochondrial function, and redox signaling pathways.
• Nutraceutical Formulation: Incorporated into advanced dietary supplement blends targeting oxidative stress management.
• Fine Chemical Synthesis: Serves as a versatile building block for creating novel sulfur-containing compounds with potential biological activity.
• Cosmeceutical Development: Investigated for use in anti-aging and skin-protectant formulations due to its derivative's antioxidant properties.

Basic Information

Product Name	1,2-Dithiolane-3-Pentanoic Acid 1-Oxide
CAS No.	6992-30-9
Molecular Formula	C8H14O3S2
Molecular Weight	222.33 g/mol
Synonyms	α-Lipoic Acid Sulfoxide; 6,8-Disulfinyloctanoic Acid; 5-(1,2-Dithiolan-3-yl)pentanoic Acid 1-Oxide; Thioctic Acid Sulfoxide; DL-6,8-Thioctic Acid Sulfoxide; 1,2-Dithiolane-3-valeric Acid 1-Oxide; R/S-Lipoic Acid Sulfoxide
EINECS	Contact for details

Quality Control

We supply 1,2-Dithiolane-3-Pentanoic Acid 1-Oxide in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.