Description

Ethyl Morpholinocarboxylate is a versatile organic building block and intermediate of significant importance in advanced chemical synthesis. Its value lies in its ability to introduce both morpholine and ester functionalities, which are key motifs in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of various drug candidates, particularly those targeting the central nervous system or requiring morpholine-based pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the morpholine ring enhances biological activity.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing protected amino-alcohol or amide-equivalent groups in multi-step synthetic routes.
• Ligand and Catalyst Preparation: Employed in the development of novel ligands for metal-catalyzed reactions or as a precursor for functionalized catalysts.
• Polymer Chemistry Modifier: Can be used to incorporate morpholine units into polymer chains, potentially modifying solubility or biological properties for specialty materials.
• Research & Development: A valuable tool for medicinal chemistry and process chemistry research in both academic and industrial settings.

Basic Information

Product Name	Ethyl Morpholinocarboxylate
CAS No.	6976-49-4
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	Ethyl Morpholine-4-carboxylate; 4-Carbethoxymorpholine; Morpholine-4-carboxylic Acid Ethyl Ester; N-Carbethoxymorpholine; 4-(Ethoxycarbonyl)morpholine; Ethyl 4-Morpholinecarboxylate; NSC 401119; N-Ethoxycarbonylmorpholine
EINECS	230-215-7

Quality Control

Our Ethyl Morpholinocarboxylate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. While typically supplied in technical or research grades, production can be aligned with cGMP principles for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4600 - 1.4700
Density (g/mL at 20°C)	1.090 - 1.130

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.