Description

5-Amino-2-Chloro-4,6-Dimethylnicotinonitrile is a versatile and high-value heterocyclic building block with a chloropyridine core. This compound matters for its role as a critical intermediate in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, ligands for catalysis, and other functional organic materials.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	5-Amino-2-Chloro-4,6-Dimethylnicotinonitrile
CAS No.	6972-36-7
Molecular Formula	C8H8ClN3
Molecular Weight	181.62 g/mol
Synonyms	2-Chloro-5-amino-4,6-dimethylnicotinonitrile; 5-Amino-2-chloro-4,6-dimethyl-3-pyridinecarbonitrile; 3-Cyano-5-amino-2-chloro-4,6-dimethylpyridine; 2-Chloro-4,6-dimethyl-5-aminonicotinonitrile; 5-Amino-2-chloro-4,6-dimethyl-3-cyanopyridine; 4,6-Dimethyl-5-amino-2-chloronicotinonitrile; 2-Chloro-5-amino-4,6-dimethyl-3-cyanopyridine
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Chloro-4,6-Dimethylnicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.