Description

(5'Ar)-1,2',3,3',5'Aβ,6',7',8',9',9'Aα,10',10'Aα-Dodecahydro-8'α-Hydroxy-3-Oxospiro[2H-Indole-2,1'(5'H)-Pyrrolo[1,2-B]Isoquinoline]-9'α-Carboxylic Acid Methyl Ester is a complex spirocyclic alkaloid derivative with significant potential as a key synthetic intermediate in advanced organic chemistry. Its intricate polycyclic structure makes it a valuable scaffold for pharmaceutical research and development, particularly in the synthesis of novel bioactive compounds. This high-purity chemical is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in complex molecule analysis.
• Academic & Institutional Research: Utilized in universities and research institutes for studying complex alkaloid chemistry, spirocyclic systems, and novel synthetic methodologies.
• Process Chemistry Development: Acts as a model compound for developing and optimizing scalable synthetic routes for complex heterocycles.
• Agrochemical Intermediate: Potential use in the synthesis of advanced, biologically active molecules for crop protection research.

Basic Information

Product Name	(5'Ar)-1,2',3,3',5'Aβ,6',7',8',9',9'Aα,10',10'Aα-Dodecahydro-8'α-Hydroxy-3-Oxospiro[2H-Indole-2,1'(5'H)-Pyrrolo[1,2-B]Isoquinoline]-9'α-Carboxylic Acid Methyl Ester
CAS No.	6872-98-6
Molecular Formula	C22H26N2O4
Molecular Weight	382.46 g/mol
Synonyms	Methyl (5'Ar)-1,2',3,3',5'Aβ,6',7',8',9',9'Aα,10',10'Aα-dodecahydro-8'α-hydroxy-3-oxospiro[2H-indole-2,1'(5'H)-pyrrolo[1,2-b]isoquinoline]-9'α-carboxylate; Spiro[indole-3,2'-pyrrolo[1,2-b]isoquinoline] derivative; 6872-98-6; UNII-7G3Q2F3W1F; 7G3Q2F3W1F; Methyl ester of the spirocyclic alkaloid acid; Pyrroloisoquinoline-indole spiro compound.
EINECS	Contact for details

Quality Control

Our (5'Ar)-1,2',3,3',5'Aβ,6',7',8',9',9'Aα,10',10'Aα-Dodecahydro-8'α-Hydroxy-3-Oxospiro[2H-Indole-2,1'(5'H)-Pyrrolo[1,2-B]Isoquinoline]-9'α-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.