Description

4-Chloro-1,6-Naphthyridine is a versatile halogenated naphthyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure and reactive chlorine substituent make it a valuable intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by acting as a core scaffold for bioactive molecules.
• Material Science: Serves as a monomer or ligand in the creation of specialized polymers, metal-organic frameworks (MOFs), and electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the naphthyridine moiety into more complex structures.
• Academic & R&D: A valuable reagent for methodological studies and exploring new reaction mechanisms in heterocyclic chemistry.

Basic Information

Product Name	4-Chloro-1,6-Naphthyridine
CAS No.	6861-84-3
Molecular Formula	C8H5ClN2
Molecular Weight	164.59 g/mol
Synonyms	4-Chloro-1,6-naphthyridine; 1,6-Naphthyridine, 4-chloro-; 4-Chloro-1,6-diazanaphthalene; 4-Chloro[1,6]naphthyridine; NSC 163044; 4-Chloro-1,6-naphthyridine (CAS 6861-84-3)
EINECS	Contact for details

Quality Control

Our 4-Chloro-1,6-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.