Description

2-Hydroxy-5-Nitronicotinic Acid is a versatile nitropyridine derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of functional groups, enabling its use in the construction of complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists, process engineers, and manufacturers operating in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging its nitropyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands used in catalysis and metal complexation.
• Organic Synthesis Research: Employed in academic and industrial R&D for studying nitration reactions and heterocyclic chemistry.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing certain azo dyes and colorants due to its nitro and carboxylic acid functionalities.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	2-Hydroxy-5-Nitronicotinic Acid
CAS No.	6854-07-5
Molecular Formula	C6H4N2O5
Molecular Weight	184.11 g/mol
Synonyms	5-Nitro-2-hydroxynicotinic Acid; 2-Hydroxy-5-nitropyridine-3-carboxylic Acid; 3-Carboxy-2-hydroxy-5-nitropyridine; 5-Nitro-2-pyridone-3-carboxylic Acid; 2-Pyridinol, 5-nitro-, 3-carboxylic acid; 5-Nitro-2(1H)-pyridone-3-carboxylic Acid; 6854-07-5 (CAS RN)
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-Nitronicotinic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.