Description

Hyoscyamine Sulfate CAS NO 6835-16-1 is a high-purity pharmaceutical-grade alkaloid salt derived from plants of the Solanaceae family. This compound is a critical active pharmaceutical ingredient (API) valued for its potent anticholinergic and antispasmodic properties. It is primarily required by manufacturers in the pharmaceutical and biotechnology sectors for the formulation of prescription medications. Our supply ensures consistent quality and reliable availability for global production needs.

Application

• Pharmaceutical API: Core active ingredient in antispasmodic and anticholinergic prescription drugs.
• Gastrointestinal Therapeutics: Used in formulations to treat irritable bowel syndrome (IBS), peptic ulcers, and intestinal colic.
• Urological Treatments: Key component in medications for urinary incontinence and bladder spasms.
• Ophthalmic Solutions: Employed in cycloplegic and mydriatic eye drops for diagnostic procedures.
• Pre-Anesthetic Medication: Used to reduce salivary and bronchial secretions before surgery.
• Analgesic Adjunct: Incorporated in certain analgesic formulations to relieve smooth muscle spasms associated with pain.
• Veterinary Medicine: Applied in veterinary pharmaceuticals for similar antispasmodic indications in animals.
• Reference Standard: Serves as a high-purity analytical standard in quality control and research laboratories.

Basic Information

Product Name	Hyoscyamine Sulfate
CAS No.	6835-16-1
Molecular Formula	(C17H23NO3)2 • H2SO4
Molecular Weight	712.85 g/mol
Synonyms	Hyoscyamine Sulphate; Atropine Sulfate (isomer); Datrine Sulfate; (3-Endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate sulfate; Levsin Sulfate; Anaspaz; Cystospaz; Donnamar Sulfate; Egacene Sulfate
EINECS	229-916-0

Quality Control

Our Hyoscyamine Sulfate is manufactured under strict quality management systems. It meets or exceeds relevant pharmacopeial standards, including USP (United States Pharmacopeia) and EP (European Pharmacopoeia) monographs where applicable. Every batch undergoes comprehensive analytical testing, including assay, identification, and impurity profiling. A Certificate of Analysis (COA) documenting all test results is provided with each shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (TLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Specific Rotation	-20° to -23° (c = 5 in H2O)
Loss on Drying	≤ 1.0%
Sulfated Ash	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with EP/USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.