Description

1,4-Dioxa-8-Azaspiro[4.5]Decan-7-One is a versatile spirocyclic lactam compound that serves as a crucial synthetic intermediate in advanced organic chemistry. Its unique bridged structure makes it a valuable building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This high-purity intermediate is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of polymers and advanced organic materials with specific functional properties.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes and inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1,4-Dioxa-8-Azaspiro[4.5]Decan-7-One
CAS No.	6813-54-3
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	8-Aza-1,4-dioxaspiro[4.5]decan-7-one; 1,4-Dioxa-8-azaspiro[4.5]decan-7-one; 7-Oxo-1,4-dioxa-8-azaspiro[4.5]decane; 2-Oxo-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid, lactone; Spirocyclic lactam ether
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-8-Azaspiro[4.5]Decan-7-One is manufactured under strict quality management systems. We provide material suitable for research and commercial synthesis, with typical purity grades exceeding 97% (by HPLC). Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles to ensure consistency and reliability for your critical processes. Certificates are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.