Description

Rotundine is a naturally occurring isoquinoline alkaloid, recognized for its significant pharmacological activity. This compound serves as a crucial intermediate and active pharmaceutical ingredient (API) in the development of therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical manufacturers, research institutions, and fine chemical suppliers engaged in neuropharmacology and analgesic drug development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of analgesic and sedative medications.
• Neurological Research: Used as a reference standard and active compound in studies related to pain pathways and neuroprotection.
• Analgesic Formulations: Incorporated into formulations for its potential pain-relieving (analgesic) properties.
• API Development: Serves as an Active Pharmaceutical Ingredient in the development of new therapeutic drugs.
• Biochemical Research: Employed in receptor-binding assays and studies of isoquinoline alkaloid activity.
• Reference Standard: Used in analytical laboratories for quality control and method validation via HPLC or LC-MS.

Basic Information

Product Name	Rotundine
CAS No.	6808-63-5
Molecular Formula	C21H25NO4
Molecular Weight	355.43 g/mol
Synonyms	L-Tetrahydropalmatine; Gindarine; Rotundin; (S)-Corydalis B; L-THP; NSC 15760; 5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine; Stephania rotunda extract alkaloid
EINECS	Contact for details

Quality Control

Our Rotundine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, residual solvent analysis, and heavy metal screening. Certificates of Analysis (COA) compliant with cGMP guidelines are available for all batches upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.