Description

Spiro[Indoline-3,3'-Pyrrolidin]-2-One CAS NO 6786-41-0 is a high-value, complex heterocyclic compound featuring a unique spirocyclic architecture that integrates indoline and pyrrolidinone motifs. This sophisticated molecular framework makes it a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Scaffold: Used extensively in drug discovery programs for constructing compound libraries and exploring structure-activity relationships (SAR) due to its three-dimensional, drug-like properties.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, leveraging its complex heterocyclic structure for novel modes of action.
• Organic Synthesis Reagent: Acts as a versatile precursor for synthesizing more complex spirocyclic and fused heterocyclic compounds in academic and industrial research.
• Material Science Precursor: Investigated for use in creating specialty polymers or organic electronic materials with unique optical or electronic properties.

Basic Information

Product Name	Spiro[Indoline-3,3'-Pyrrolidin]-2-One
CAS No.	6786-41-0
Molecular Formula	C11H12N2O
Molecular Weight	188.23 g/mol
Synonyms	1'-Azaspiro[indoline-3,3'-pyrrolidin]-2-one; 1-Azaspiro[4.4]nonane-2,6-dione (incorrect but related); Spiro[indoline-3,3'-pyrrolidine]-2-one; 2H,2'H-Spiro[indole-3,3'-pyrrolidin]-2-one; 1,2-Dihydrospiro[3H-indole-3,3'-pyrrolidin]-2-one; (2-Oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidin]); Spiro[indoline-3,3'-pyrrolidin]-2-one hydrochloride (salt form).
EINECS	Contact for details

Quality Control

Our Spiro[Indoline-3,3'-Pyrrolidin]-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.