Description

Uridine, 3',5'-Diacetate is a key protected nucleoside derivative, essential for advanced organic synthesis and pharmaceutical research. This compound serves as a critical building block for the controlled synthesis of oligonucleotides and modified RNA analogs, enabling precise molecular construction. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, nucleotide chemistry, and the development of therapeutic nucleic acids.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a protected monomer for the solid-phase or solution-phase synthesis of RNA and modified oligonucleotides.
• Biochemical Research: Employed in enzymatic studies and as a substrate for investigating nucleotide metabolism and related pathways.
• Prodrug Development: Facilitates the creation of prodrug forms of nucleoside therapeutics to enhance bioavailability and stability.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Uridine, 3',5'-Diacetate
CAS No.	6773-48-4
Molecular Formula	C13H16N2O8
Molecular Weight	328.27 g/mol
Synonyms	3',5'-Di-O-acetyluridine; 2',3',5'-Tri-O-acetyluridine (common misnomer); Uridine 3',5'-diacetate; 1-[(2R,3R,4R,5R)-3,4-Diacetoxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 3',5'-Diacetyluridine; Acetylated Uridine; Protected Uridine Derivative
EINECS	Contact for details

Quality Control

Our Uridine, 3',5'-Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.