Description

2-(2-Chlorobenzylidene)Malonic Acid Diethyl Ester is a versatile organic intermediate characterized by its reactive diethyl malonate and chlorobenzylidene functional groups. This compound matters for its role as a key building block in the synthesis of complex heterocyclic and fine chemical structures. It is primarily needed by research and development chemists, as well as production units in the pharmaceutical and agrochemical industries, for constructing active pharmaceutical ingredients (APIs) and specialized crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those with heterocyclic frameworks.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for molecular diversification.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for Knoevenagel condensation reactions and the construction of complex organic molecules.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other specialty chemicals requiring precise molecular architecture.
• Material Science Precursor: Investigated for use in creating organic ligands and monomers for advanced polymeric materials.

Basic Information

Product Name	2-(2-Chlorobenzylidene)Malonic Acid Diethyl Ester
CAS No.	6768-20-3
Molecular Formula	C₁₄H₁₅ClO₄
Molecular Weight	282.72 g/mol
Synonyms	Diethyl 2-[(2-chlorophenyl)methylene]malonate; Diethyl (2-Chlorobenzylidene)malonate; 2-(2-Chlorobenzylidene)propanedioic acid diethyl ester; Ethyl 2-(2-chlorobenzylidene)malonate; Propanedioic acid, 2-[(2-chlorophenyl)methylene]-, diethyl ester; (2-Chlorobenzylidene)malonic acid diethyl ester; NSC 403697
EINECS	Contact for details

Quality Control

Our 2-(2-Chlorobenzylidene)Malonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.