Description

Methyl 2-O,3-O,5-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Mannofuranoside is a highly functionalized, protected carbohydrate derivative, specifically a silylated mannose analog. This compound is a crucial synthetic intermediate, valued for its role in constructing complex oligosaccharides and glycoconjugates with precise stereochemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical, biotechnology, and fine chemical sectors for advanced glycosylation reactions and the development of carbohydrate-based therapeutics.

Application

• Glycochemistry Research: A key protected building block for the stereoselective synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediates: Used in the development of carbohydrate-based drugs, including antiviral agents, antibiotics, and vaccine components.
• Glycoconjugate Synthesis: Essential for creating glycoproteins, glycolipids, and other biologically active conjugates for biochemical studies.
• Chemical Biology Probes: Serves as a precursor for labeled sugars used to study carbohydrate metabolism and cell-surface interactions.
• Process Development: Employed in scaling up synthetic routes for high-value fine chemicals and active pharmaceutical ingredients (APIs).
• Standards and Reference Materials: Used as a high-purity analytical standard in quality control laboratories for carbohydrate analysis.

Basic Information

Product Name	Methyl 2-O,3-O,5-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Mannofuranoside
CAS No.	6737-01-5
Molecular Formula	C19H46O6Si4
Molecular Weight	482.90 g/mol
Synonyms	Methyl α-D-Mannofuranoside 2,3,5,6-Tetrakis-O-(trimethylsilyl) Ether; α-D-Mannofuranoside, methyl 2,3,5,6-tetrakis-O-(trimethylsilyl)-; Methyl 2,3,5,6-tetra-O-trimethylsilyl-α-D-mannofuranoside; TMS-protected Methyl α-D-Mannofuranoside; Tetrakis-O-TMS Methyl α-D-Mannofuranoside; Per-O-trimethylsilylated Methyl Mannoside; 6737-01-5; Methyl α-D-mannofuranoside 2,3,5,6-tetrakis(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our Methyl 2-O,3-O,5-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Mannofuranoside is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Anhydrous basis)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.