Description

(4-Methoxyphenoxy)Trimethylsilane is a specialized organosilicon reagent featuring a protected phenolic ether functionality. This compound is valued for its role as a versatile synthetic intermediate and protecting group in advanced organic synthesis. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly where protection of phenolic hydroxyl groups is required during multi-step reactions.
• Agrochemical Synthesis: Serves as a key building block in the development of herbicides, fungicides, and other crop protection agents.
• Liquid Crystal & OLED Materials: Acts as a precursor in the manufacture of advanced electronic materials for displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce silane and aromatic ether groups into polymer backbones, altering material properties like solubility and thermal stability.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for biaryl ether formation.
• Silyl Protecting Group: The trimethylsilyl (TMS) group protects reactive sites, allowing selective transformations elsewhere on the molecule, which is later cleaved under mild conditions.

Basic Information

Product Name	(4-Methoxyphenoxy)Trimethylsilane
CAS No.	6689-38-9
Molecular Formula	C10H16O2Si
Molecular Weight	196.32 g/mol
Synonyms	1-Methoxy-4-(trimethylsilyloxy)benzene; p-Methoxyphenoxytrimethylsilane; Trimethyl(4-methoxyphenoxy)silane; 4-Methoxyphenyl trimethylsilyl ether; Silane, trimethyl(4-methoxyphenoxy)-; (p-Methoxyphenoxy)trimethylsilane; 4-(Trimethylsilyloxy)anisole
EINECS	229-749-7

Quality Control

Our (4-Methoxyphenoxy)Trimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.