Description

α-Cyano-3,4-Dihydro-1(2H)-Quinolineacrylic Acid Ethyl Ester is a versatile heterocyclic building block and synthetic intermediate of significant importance in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which is crucial for constructing complex pharmacophores and functional materials. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of quinoline-based drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, light-emitting materials, and advanced polymers due to its electron-accepting cyano and conjugated quinoline groups.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags or molecular probes to study biological processes.
• Academic & R&D: Fundamental reagent in methodological organic chemistry research for studying cyclization reactions and heterocycle formation.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals and performance additives.

Basic Information

Product Name	α-Cyano-3,4-Dihydro-1(2H)-Quinolineacrylic Acid Ethyl Ester
CAS No.	6687-86-1
Molecular Formula	C₁₅H₁₆N₂O₂
Molecular Weight	256.30 g/mol
Synonyms	Ethyl α-Cyano-3,4-dihydro-1(2H)-quinolineacrylate; 2-Cyano-3-(3,4-dihydro-1(2H)-quinolyl)acrylic Acid Ethyl Ester; 2-Cyano-3-(1,2,3,4-tetrahydroquinolin-1-yl)acrylic Acid Ethyl Ester; (2E)-2-Cyano-3-(1,2,3,4-tetrahydroquinolin-1-yl)prop-2-enoic Acid Ethyl Ester; Ethyl (2E)-2-cyano-3-(1,2,3,4-tetrahydroquinolin-1-yl)acrylate; Quinolineacrylic Acid Ethyl Ester Derivative
EINECS	Contact for details

Quality Control

Our α-Cyano-3,4-Dihydro-1(2H)-Quinolineacrylic Acid Ethyl Ester is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure consistent quality and reliable performance in your synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.