Description

2-Chloropyridine-5-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate essential for advanced synthesis. Its core value proposition lies in its dual reactive sites, enabling the efficient construction of complex sulfonamide and heterocyclic scaffolds. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Functional Material Precursor: Serves as a starting material for dyes, pigments, and organic electronic materials.
• Chemical Research & Development: A versatile reagent for introducing the 2-chloro-5-sulfonyl chloride moiety into complex molecules in medicinal and process chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of proprietary compounds and advanced intermediates under cGMP conditions where required.

Basic Information

Product Name	2-Chloropyridine-5-Sulfonyl Chloride
CAS No.	6684-39-5
Molecular Formula	C5H3Cl2NO2S
Molecular Weight	212.05 g/mol
Synonyms	5-Chlorosulfonyl-2-chloropyridine; 2-Chloro-5-pyridinesulfonyl chloride; 2-Chloropyridine-5-sulphonyl chloride; 5-(Chlorosulfonyl)-2-chloropyridine; Pyridine, 2-chloro-5-sulfonyl chloride; 2-Chloro-5-chlorosulfonylpyridine; 2-Chloropyridine-5-sulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Chloropyridine-5-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.