Description

2-Chloropyridine-3-Sulfonyl Chloride is a versatile and highly reactive bifunctional intermediate essential for advanced organic synthesis. Its dual functionality makes it a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating sulfonamides and other sulfonyl-containing derivatives.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for creating sulfonamide-based pharmacophores with potential therapeutic activity.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the pyridine-sulfonyl chloride scaffold.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of functional polymers and advanced materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Chemical Biology Probes: Utilized to create activity-based probes and other tools for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Chloropyridine-3-Sulfonyl Chloride
CAS No.	6684-06-6
Molecular Formula	C5H3Cl2NO2S
Molecular Weight	212.05 g/mol
Synonyms	3-Chlorosulfonyl-2-chloropyridine; 2-Chloro-3-pyridinesulfonyl chloride; 2-Chloropyridine-3-sulphonyl chloride; 3-Pyridinesulfonyl chloride, 2-chloro-; 2-Chloro-3-pyridylsulfonyl chloride; 2-Chloro-3-sulfonylchloridopyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloropyridine-3-Sulfonyl Chloride is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.