Description

1-Ethyl-2,3,4,9-tetrahydro-1H-β-carboline is a heterocyclic organic compound belonging to the β-carboline alkaloid class, a structure of significant interest in medicinal chemistry. This compound serves as a versatile synthetic intermediate and a crucial scaffold for developing novel bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery, particularly for exploring neurological and oncological targets.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of more complex β-carboline derivatives with potential therapeutic applications.
• Neurological Research: Investigated as a core structure for developing ligands targeting serotonin receptors, monoamine oxidases (MAOs), and benzodiazepine receptors.
• Oncology Research: Serves as a precursor for compounds studied for their anti-proliferative and apoptosis-inducing properties against various cancer cell lines.
• Chemical Biology: Used as a molecular probe to study protein-ligand interactions and enzyme inhibition mechanisms.
• Organic Synthesis: Employed in academic and industrial R&D for constructing complex nitrogen-containing heterocycles.
• Reference Standard: Utilized as an analytical standard in quality control and method development for pharmaceutical analysis.

Basic Information

Product Name	1-Ethyl-2,3,4,9-tetrahydro-1H-β-carboline
CAS No.	6678-86-0
Molecular Formula	C₁₃H₁₆N₂
Molecular Weight	200.28 g/mol
Synonyms	1-Ethyl-1,2,3,4-tetrahydro-9H-β-carboline; 1-Ethyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole; 9H-Pyrido[3,4-b]indole, 1-ethyl-1,2,3,4-tetrahydro-; Norharman, 1-ethyl-1,2,3,4-tetrahydro-; 1-Ethyltetrahydro-β-carboline; 1-Ethyl-THBC; NSC 172925; 1-Ethyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
EINECS	Contact for details

Quality Control

Our 1-Ethyl-2,3,4,9-tetrahydro-1H-β-carboline is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.