Description

tert-Butyl Phenyl Carbonate is a versatile organic carbonate ester, widely utilized as a key intermediate in advanced chemical synthesis. Its primary value lies in its role as a robust protecting group for phenols and as a reagent for introducing the tert-butoxycarbonyl (Boc) moiety, which is critical for stability in multi-step processes. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: A crucial reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for protecting phenolic hydroxyl groups during complex reaction sequences.
• Agrochemical Synthesis: Used in the manufacturing of advanced pesticides and herbicides where the tert-butyl carbonate group provides necessary stability and reactivity.
• Polymer Chemistry: Serves as a monomer or modifying agent in the production of specialty polycarbonates and other high-performance polymers.
• Organic Synthesis Reagent: Employed as a tert-butoxycarbonylation agent for amines, alcohols, and other nucleophiles in laboratory and pilot-scale preparations.
• Peptide Chemistry: Functions as a protecting group in solid-phase peptide synthesis (SPPS) to safeguard specific amino acid side chains.
• Material Science Research: Investigated for use in developing novel organic frameworks and surface modification agents.

Basic Information

Product Name	tert-Butyl Phenyl Carbonate
CAS No.	6627-89-0
Molecular Formula	C11H14O3
Molecular Weight	194.23 g/mol
Synonyms	Phenyl tert-Butyl Carbonate; tert-Butyloxycarbonyloxybenzene; Boc-Phenyl; BOC-O-Ph; Carbonochloridic Acid, Phenyl Ester, 1,1-Dimethylethyl Ester; Phenyl Chloroformate, tert-Butyl Ester; t-Butyl Phenyl Carbonate; 1,1-Dimethylethyl Phenyl Carbonate
EINECS	229-596-7

Quality Control

Our tert-Butyl Phenyl Carbonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (IR, NMR), to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.05 g/cm³ at 20°C
Refractive Index	~1.48 at 20°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.