Description

4,6-Dimethylnicotinonitrile is a versatile nitrile-substituted pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex heterocyclic molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing nitrile group.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to diverse R&D projects.

Basic Information

Product Name	4,6-Dimethylnicotinonitrile
CAS No.	6623-21-8
Molecular Formula	C8H8N2
Molecular Weight	132.16 g/mol
Synonyms	3-Cyano-4,6-dimethylpyridine; 4,6-Dimethyl-3-pyridinecarbonitrile; 4,6-Dimethyl-3-cyanopyridine; Nicotinonitrile, 4,6-dimethyl-; 3-Pyridinecarbonitrile, 4,6-dimethyl-; 4,6-Lutidine-3-carbonitrile
EINECS	229-586-8

Quality Control

Our 4,6-Dimethylnicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against established specifications. Certificates of Analysis (COA) documenting all test results are provided with every shipment. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.