Description

4-Pyridineacetic Acid Hydrochloride is a versatile heterocyclic building block and organic salt of significant importance in advanced chemical synthesis. Its value lies in its dual functionality, featuring both a pyridine nitrogen and a reactive acetic acid moiety, which makes it a key intermediate for constructing complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Bioconjugation and Linker Chemistry: The carboxylic acid group enables its use as a linker molecule for attaching functional groups to proteins, peptides, or other biomolecules in bioconjugation applications.
• Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and other functional polymeric materials.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development, validation, and quality control testing.

Basic Information

Product Name	4-Pyridineacetic Acid Hydrochloride
CAS No.	6622-91-9
Molecular Formula	C7H7NO2·HCl
Molecular Weight	173.60 g/mol (Free base: 137.14 g/mol)
Synonyms	4-Pyridylacetic Acid Hydrochloride; (4-Pyridinyl)acetic Acid Hydrochloride; 2-(Pyridin-4-yl)acetic Acid Hydrochloride; PAAH; p-Pyridineacetic Acid HCl; 4-Carboxymethylpyridine Hydrochloride; Isonicotinic Acid, ω-Hydroxy-, Hydrochloride (related); EINECS 229-596-8
EINECS	229-596-8

Quality Control

Our 4-Pyridineacetic Acid Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identification. Specifications can be aligned with customer requirements for specific applications, including those under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.