Description

2-Chloro-3-Cyanopyridine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a chloro and a cyano substituent, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized pyridine derivatives for electronic materials, organic semiconductors, and liquid crystals.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and enzyme inhibition.

Basic Information

Product Name	2-Chloro-3-Cyanopyridine
CAS No.	6602-54-6
Molecular Formula	C6H3ClN2
Molecular Weight	138.56 g/mol
Synonyms	3-Cyano-2-chloropyridine; 2-Chloro-3-pyridinecarbonitrile; 2-Chloronicotinonitrile; 2-Chloro-3-cyanopyridine; 3-Pyridinecarbonitrile, 2-chloro-; 2-Chloropyridine-3-carbonitrile
EINECS	229-559-1

Quality Control

Our 2-Chloro-3-Cyanopyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.