Description

n-(Dichloroboryl)Hexamethyldisilazane is a highly reactive organoboron reagent, specifically a chloroborane derivative protected by a hexamethyldisilazane (HMDS) group. This compound matters for its role as a versatile precursor and protecting agent in advanced synthetic chemistry, enabling the controlled introduction of boron functionalities. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for synthesizing complex molecules and novel polymers.

Application

• Suzuki-Miyaura Cross-Coupling Precursor: Serves as a key intermediate for generating aryl- and vinyl-boronic acids/esters, crucial for constructing biaryl motifs in active pharmaceutical ingredients (APIs).
• Polymer & Materials Science: Used in the synthesis of boron-containing polymers, resins, and advanced ceramic precursors for high-performance materials.
• Organic Synthesis Reagent: Acts as a Lewis acid catalyst or a boron-protecting group transfer agent in stereoselective transformations and functional group manipulations.
• Agrochemical Intermediate: Employed in the research and development of novel herbicides and fungicides that incorporate boron heterocycles.
• Surface Modification Agent: Utilized for the functionalization of silica and other metal oxide surfaces to alter surface properties for chromatography or composite materials.

Basic Information

Product Name	n-(Dichloroboryl)Hexamethyldisilazane
CAS No.	6591-26-0
Molecular Formula	C9H24BCl2NSi2
Molecular Weight	280.18 g/mol
Synonyms	1,1,1,3,3,3-Hexamethyldisilazane Boron Dichloride; (Dichloroboryl)bis(trimethylsilyl)amine; HMDS-Boron Dichloride; B,B-Dichloro-N-(trimethylsilyl)-N-(trimethylsilyl)aminoborane; N-(Dichloroboryl)-1,1,1,3,3,3-hexamethyldisilazane; Boron dichloride hexamethyldisilazane complex; BCl2-HMDS
EINECS	Contact for details

Quality Control

Every batch of n-(Dichloroboryl)Hexamethyldisilazane is manufactured and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure consistency and reliability for your critical synthetic applications. Our quality commitment aligns with cGMP principles where applicable, supporting development from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC or NMR)	≥ 95.0%
Chloride Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.