Description

Tryptophanethylester CAS NO 6519-66-0 is a protected derivative of the essential amino acid L-tryptophan, where the carboxylic acid group is esterified with ethanol. This modification is crucial for peptide synthesis and pharmaceutical research, as it protects the amino acid during coupling reactions while maintaining the reactivity of the amine group. This compound is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers involved in developing bioactive peptides, peptidomimetics, and novel therapeutic agents.

Application

• Peptide Synthesis: Serves as a key building block (amino acid derivative) in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies of enzyme-substrate interactions, receptor binding, and metabolic pathways involving tryptophan.
• Protecting Group Strategy: The ethyl ester group protects the carboxyl functionality, allowing selective reactions at other sites of the molecule.
• Fine Chemical Production: Acts as a precursor for more complex chiral molecules and specialty chemicals.

Basic Information

Item	Details
Product Name	Tryptophanethylester
CAS No.	6519-66-0
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	L-Tryptophan ethyl ester; Ethyl L-tryptophanate; Tryptophan ethyl ester; (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid ethyl ester; H-Trp-OEt; Ethyl α-amino-1H-indole-3-propanoate; Ethyl 2-amino-3-(3-indolyl)propionate
EINECS	Contact for details

Quality Control

Our Tryptophanethylester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis applications. A Certificate of Analysis (COA) detailing identity, purity (by HPLC), and specific rotation is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Specific Rotation [α]20/D	+30.0° to +33.0° (c=1 in acetic acid)
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.