Description

8-[(2-Pyridylmethyl)Thio]-3,7-Dihydro-1,3-Dimethyl-6-Thio-1H-Purin-2-One is a high-purity, specialized purine derivative with a pyridylmethylthio substituent, offering a unique chemical scaffold for advanced synthesis. This compound is valued for its role as a critical intermediate in the research and development of novel pharmaceutical agents, particularly in the fields of oncology and neurology. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing targeted small-molecule therapies and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential adenosine receptor antagonists and other purine-based drug candidates.
• Biochemical Research: Used as a reference standard or precursor in studies investigating enzyme inhibition, signal transduction pathways, and receptor-ligand interactions.
• Medicinal Chemistry: Provides a versatile core structure for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	8-[(2-Pyridylmethyl)Thio]-3,7-Dihydro-1,3-Dimethyl-6-Thio-1H-Purin-2-One
CAS No.	6493-43-2
Molecular Formula	C₁₄H₁₅N₅OS₂
Molecular Weight	333.43 g/mol
Synonyms	8-[(Pyridin-2-ylmethyl)sulfanyl]-3,7-dihydro-1,3-dimethyl-6-sulfanylidene-1H-purine-2-one; 8-[(2-Pyridinylmethyl)thio]-3,7-dihydro-1,3-dimethyl-6-thioxo-1H-purine-2-one; 1,3-Dimethyl-8-[(2-pyridylmethyl)thio]-6-thioxanthine; 8-(2-Pyridylmethylthio)theophylline; 6-Thio-8-[(2-pyridylmethyl)thio]theophylline; 8-(Pyrid-2-ylmethylmercapto)theophylline; 6493-43-2
EINECS	Contact for details

Quality Control

Our 8-[(2-Pyridylmethyl)Thio]-3,7-Dihydro-1,3-Dimethyl-6-Thio-1H-Purin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.