Description

3β,5α-Tetrahydronorethisterone is a synthetic steroid derivative and a key pharmaceutical intermediate. This compound is valued for its role in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of hormonal therapies and other steroid-based drugs.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of steroidal drugs and hormonal agents.
• Research & Development: Used in medicinal chemistry research for exploring new therapeutic compounds and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of steroid APIs.

Basic Information

Product Name	3β,5α-Tetrahydronorethisterone
CAS No.	6424-05-1
Molecular Formula	C₂₀H₃₀O₂
Molecular Weight	302.45 g/mol
Synonyms	19-Nor-17α-pregn-4-en-20-yn-3-one, 17β-hydroxy-, (3β,5α)-; 3β-Hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one; 5α-Dihydronorethisterone; 5α-Dihydro-19-norethisterone; 3β,5α-Tetrahydro-19-norethisterone; 19-Nor-17α-pregn-4-en-20-yn-3β-ol; Norethisterone 3β,5α-tetrahydro derivative
EINECS	Contact for details

Quality Control

Our 3β,5α-Tetrahydronorethisterone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.