Description

2-Chloroethyl 2,3,4-Tri-o-Acetyl-β-D-Glucopyranosiduronic Acid Methyl Ester is a key protected intermediate in synthetic carbohydrate and medicinal chemistry. This compound matters because it provides a versatile, reactive handle for the controlled synthesis of complex glycosides and glycoconjugates, which are critical in drug discovery and biochemical research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity building block to develop novel therapeutics, diagnostic agents, and advanced biomaterials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of glycosidase inhibitors, antiviral agents, and other carbohydrate-based active pharmaceutical ingredients (APIs).
• Glycoconjugate Synthesis: Used for the controlled preparation of glycoconjugates for vaccine development, targeted drug delivery systems, and diagnostic probes.
• Biochemical Research: Acts as a substrate or intermediate in enzymatic studies and for probing carbohydrate-protein interactions.
• Glycosylation Reagent: Employed in stereoselective glycosylation reactions to construct complex oligosaccharide structures.
• Fine Chemical Production: A valuable building block for manufacturing specialty chemicals with specific chiral and functional properties.
• Academic Research: Utilized in universities and research institutes for developing new synthetic methodologies in carbohydrate chemistry.

Basic Information

Product Name	2-Chloroethyl 2,3,4-Tri-o-Acetyl-β-D-Glucopyranosiduronic Acid Methyl Ester
CAS No.	6386-29-4
Molecular Formula	C₁₅H₂₁ClO₁₁
Molecular Weight	412.77 g/mol
Synonyms	Methyl (2,3,4-tri-O-acetyl-β-D-glucopyranosyluronate) 2-chloroethyl glycoside; 2-Chloroethyl 2,3,4-Tri-O-acetyl-β-D-glucopyranosiduronic Acid Methyl Ester; β-D-Glucopyranosiduronic acid, 2-chloroethyl 2,3,4-tri-O-acetyl-, methyl ester; Methyl 2-chloroethyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate; Glucuronic acid derivative, 2-chloroethyl triacetyl methyl ester; 6386-29-4; 2-Chloroethyl tri-O-acetyl-β-D-glucopyranosiduronate methyl ester
EINECS	Contact for details

Quality Control

Our 2-Chloroethyl 2,3,4-Tri-o-Acetyl-β-D-Glucopyranosiduronic Acid Methyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.