Description

Dimethyl L-Aspartate is a high-purity, chiral ester derivative of the amino acid L-aspartic acid. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceuticals, fine chemicals, and bioactive peptides. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries where stereochemical purity is paramount.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs), including protease inhibitors and other therapeutics.
• Peptide Synthesis: Used as a protected aspartic acid derivative in solid-phase and solution-phase peptide synthesis.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in asymmetric catalytic reactions to introduce chiral centers.
• Agrochemicals: Intermediate in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Flavor & Fragrance Industry: Potential precursor for the synthesis of certain flavor compounds and aroma chemicals.
• Biochemical Research: Used in enzymatic studies and as a standard in analytical method development for amino acid analysis.
• Cosmetic Ingredients: Intermediate for the synthesis of certain conditioning agents and skin-active ingredients.

Basic Information

Product Name	Dimethyl L-Aspartate
CAS No.	6384-18-5
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	L-Aspartic Acid Dimethyl Ester; (S)-Dimethyl 2-Aminobutanedioate; H-Asp(OMe)-OMe; Dimethyl (S)-2-Aminosuccinate; (S)-1,4-Dimethoxy-1,4-dioxobutan-2-aminium; Aspartic Acid Dimethyl Ester, L-; Methyl L-Aspartate
EINECS	228-980-5

Quality Control

Our Dimethyl L-Aspartate is manufactured under a strict quality management system. Each batch is tested to ensure high chemical and chiral purity, meeting the rigorous standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), specific rotation, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Specific Rotation [α]20/D	-22.0° to -25.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.