Description

2-Chloro-5-Amino Pyridine is a versatile halogenated aminopyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive chlorine atom and an amino group, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by the pharmaceutical and agrochemical industries for the development of active ingredients, as well as by research institutions for material science applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral, and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for functional polymers, dyes, and electronic materials where the pyridine moiety imparts specific electronic properties.
• Chemical Research: A valuable reagent for heterocyclic and medicinal chemistry research, enabling novel ring formations and derivatizations.
• Custom Synthesis: Employed by fine chemical manufacturers for the contract synthesis of complex, customer-specific molecules.

Basic Information

Product Name	2-Chloro-5-Amino Pyridine
CAS No.	6350-93-6
Molecular Formula	C5H5ClN2
Molecular Weight	128.56 g/mol
Synonyms	5-Amino-2-chloropyridine; 2-Chloro-5-pyridinamine; 2-Chloro-5-aminopyridine; 5-Amino-2-chloro-pyridine; 2-Chloro-5-pyridylamine; 2-Chloropyridin-5-amine; 5-Amino-2-chloropyridine; 2-Chloro-5-aminopyridine
EINECS	228-748-9

Quality Control

Our 2-Chloro-5-Amino Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.