Description

1H-Imidazole-1-Acetic Acid, 4-Methyl-, Ethyl Ester is a versatile and high-purity chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its functionalized imidazole core, which serves as a critical building block for the development of complex molecules. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications ranging from drug discovery to material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and plant growth regulators due to its bioactive imidazole moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics Research: Employed in medicinal chemistry for constructing imidazole-based scaffolds that mimic peptide structures.
• Specialty Polymer Modification: Utilized to introduce functional imidazole groups into polymer chains, enhancing properties like adhesion or biocompatibility.
• Chemical Biology Probes: Acts as a building block for fluorescent tags and molecular probes used in diagnostic and cellular imaging applications.

Basic Information

Item	Details
Product Name	1H-Imidazole-1-Acetic Acid, 4-Methyl-, Ethyl Ester
CAS No.	6338-47-2
Molecular Formula	C8H12N2O2
Molecular Weight	168.19 g/mol
Synonyms	Ethyl 4-Methyl-1H-imidazole-1-acetate; 4-Methyl-1H-imidazole-1-acetic Acid Ethyl Ester; 1-Carbethoxymethyl-4-methylimidazole; 4-Methylimidazole-1-acetic Acid Ethyl Ester; 1-(Ethoxycarbonylmethyl)-4-methylimidazole; 4-Methyl-1-imidazoleacetic Acid Ethyl Ester; NSC 163063
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-1-Acetic Acid, 4-Methyl-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.