Description

6-Bromonicotinic Acid is a versatile brominated heterocyclic building block essential for modern organic synthesis. Its core value lies in its dual functionality, featuring both a reactive bromine atom and a carboxylic acid group, enabling precise molecular construction. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	6-Bromonicotinic Acid
CAS No.	6311-35-9
Molecular Formula	C6H4BrNO2
Molecular Weight	202.01 g/mol
Synonyms	2-Bromo-5-pyridinecarboxylic Acid; 5-Bromopyridine-2-carboxylic Acid; 6-Bromopyridine-3-carboxylic Acid; Nicotinic Acid, 6-Bromo-; 6-Bromo-3-pyridinecarboxylic Acid; 2-Carboxy-5-bromopyridine
EINECS	Contact for details

Quality Control

Our 6-Bromonicotinic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	205 - 210 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.