Description

4-(Hydroxymethyl)Phenyl Acetate is a versatile aromatic ester compound that serves as a valuable intermediate in advanced organic synthesis. Its bifunctional structure, featuring both a phenolic acetate and a benzylic alcohol, makes it a critical building block for creating complex molecules with tailored properties. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty polymer industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and fungicides, where its aromatic core is incorporated into bioactive molecules.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or modifying agent for producing specialty polymers, resins, and liquid crystal materials.
• Organic Synthesis Building Block: Employed in protecting group strategies and cross-coupling reactions to construct complex aromatic systems in R&D laboratories.
• UV Absorber & Stabilizer Precursor: Acts as a starting material for synthesizing compounds used in plastics and coatings to enhance light stability.
• Fine Chemical Production: Utilized in the custom synthesis of dyes, fragrances, and other performance chemicals.

Basic Information

Product Name	4-(Hydroxymethyl)Phenyl Acetate
CAS No.	6309-46-2
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	p-(Acetoxymethyl)phenol; 4-(Acetoxymethyl)phenol; 4-Hydroxybenzyl Acetate; p-Hydroxybenzyl Acetate; (4-Hydroxyphenyl)methyl Acetate; Acetic Acid 4-Hydroxybenzyl Ester; HMPA (context-specific abbreviation); Benzyl alcohol, p-hydroxy-, acetate
EINECS	228-618-0

Quality Control

Our 4-(Hydroxymethyl)Phenyl Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed chromatographic data for each lot. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.