Description

(2,6-Dioxo-Piperidin-4-Yl)-Acetic Acid is a high-purity organic compound that serves as a versatile and critical building block in advanced chemical synthesis. Its unique glutarimide-acetic acid structure makes it a valuable intermediate for the development of pharmaceuticals and fine chemicals. This product is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality raw materials for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing glutarimide or succinimide moieties.
• Proteasome Inhibitor Research: Used in the research and development of novel proteasome inhibitors for potential therapeutic applications.
• Fine Chemical Synthesis: Serves as a precursor for creating complex molecules used in agrochemicals, dyes, and functional materials.
• Bioconjugation & Linker Chemistry: The carboxylic acid and imide functionalities allow for its use as a spacer or linker in bioconjugation and polymer chemistry.
• Academic & R&D Laboratories: Employed in medicinal chemistry and organic synthesis research for constructing novel heterocyclic compounds.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom intermediates for clients.

Basic Information

Product Name	(2,6-Dioxo-Piperidin-4-Yl)-Acetic Acid
CAS No.	6258-28-2
Molecular Formula	C7H9NO4
Molecular Weight	171.15 g/mol
Synonyms	4-(Carboxymethyl)-2,6-piperidinedione; 4-(Carboxymethyl)glutarimide; 4-(Carboxymethyl)-2,6-dioxopiperidine; 2,6-Dioxo-4-piperidineacetic acid; Glutarimide-4-acetic acid; 4-Acetic acid-2,6-piperidinedione; (2,6-Dioxopiperidin-4-yl)acetic acid
EINECS	228-416-7

Quality Control

Our (2,6-Dioxo-Piperidin-4-Yl)-Acetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.