Description

2-Bromo-1-Pyridin-4-Ylethanone is a versatile brominated ketone building block characterized by its reactive bromomethyl ketone group adjacent to a pyridine ring. This compound is crucial for facilitating efficient carbon-carbon bond formation and heterocyclic synthesis in advanced chemical research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of complex molecules, including potential active pharmaceutical ingredients (APIs) and specialized agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the construction of complex nitrogen-containing heterocycles for drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactive site for molecular diversification.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized pyridine-based ligands used in catalytic systems.
• Material Science Research: Employed in the synthesis of functional organic molecules and monomers for advanced polymeric materials.
• Bioconjugation Chemistry: Its reactive bromoacetyl group can be utilized for labeling and modifying biomolecules in biochemical research.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	2-Bromo-1-Pyridin-4-Ylethanone
CAS No.	6221-13-2
Molecular Formula	C7H6BrNO
Molecular Weight	200.04 g/mol
Synonyms	4-Pyridyl Bromomethyl Ketone; 2-Bromo-1-(4-Pyridinyl)Ethanone; 4-Acetylpyridine Bromide; 4-Acetylpyridinium Bromide; 2-Bromo-1-(pyridin-4-yl)ethan-1-one; α-Bromo-4-acetylpyridine; p-Acetylpyridyl Bromide; Bromomethyl 4-Pyridyl Ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Pyridin-4-Ylethanone is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.