Description

(S)-Benzyl 1-Hydroxy-4-Methylpentan-2-Ylcarbamate is a chiral, non-proteinogenic amino acid derivative featuring a protected carbamate and a hydroxyl group. This compound matters as a versatile and high-purity building block for the synthesis of complex molecules, offering precise stereochemical control. It is primarily needed by researchers and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs and protease inhibitors.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry.
• Chemical Biology Research: Serves as a building block for designing enzyme inhibitors, molecular probes, and bioactive compounds.
• Asymmetric Synthesis: Employed in the preparation of enantiomerically pure compounds for medicinal chemistry and catalysis studies.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	(S)-Benzyl 1-Hydroxy-4-Methylpentan-2-Ylcarbamate
CAS No.	6216-61-1
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	(S)-Benzyl (1-hydroxy-4-methylpentan-2-yl)carbamate; (S)-2-((Benzyloxycarbonyl)amino)-4-methylpentanoic acid, 1-hydroxy derivative; (S)-N-Cbz-4-Methyl-2-hydroxyvaline benzyl ester; (S)-Benzyl N-(1-hydroxy-4-methylpentan-2-yl)carbamate; (S)-1-Hydroxy-4-methyl-2-((((phenylmethoxy)carbonyl)amino)pentane; Z-(S)-Hmv-OH (Benzyl ester); (S)-Cbz-Hmv-OH (Benzyl ester)
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 1-Hydroxy-4-Methylpentan-2-Ylcarbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.