Description

Quinine Bisulfate Heptahydrate is a high-purity, crystalline salt form of the naturally occurring alkaloid quinine. This compound is valued for its precise chemical properties and serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate. It is essential for manufacturers and research institutions in the pharmaceutical, analytical chemistry, and fine chemical sectors requiring a reliable source of this specific quinine derivative.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments and the quantification of quinine in drug formulations and raw materials.
• API Intermediate: Serves as a key precursor in the synthesis of antimalarial and other therapeutic agents.
• Analytical Chemistry: Employed as a reagent in laboratory research, method development, and quality control testing.
• Bittering Agent: Used in the food and beverage industry, particularly in tonic water production, where a consistent and pure bitter flavor profile is required.
• Chemical Research: Acts as a chiral building block or starting material in organic synthesis and asymmetric catalysis studies.
• Diagnostic Reagents: May be utilized in the formulation of specific clinical diagnostic kits and reagents.

Basic Information

Product Name	Quinine Bisulfate Heptahydrate
CAS No.	6183-68-2
Molecular Formula	C20H24N2O2 • H2SO4 • 7H2O
Molecular Weight	548.59 g/mol (Heptahydrate)
Synonyms	Quinine Hydrogen Sulfate Heptahydrate; Quinine Acid Sulfate Heptahydrate; Quinine Sulfate Hemisulfate Salt Heptahydrate; (8S,9R)-6'-Methoxycinchonan-9-ol Sulfate (1:1) Heptahydrate; Cinchonan-9-ol, 6'-methoxy-, (8S,9R)-, sulfate (1:1) (salt), heptahydrate; Quinine Hemisulfate Heptahydrate
EINECS	Contact for details

Quality Control

Our Quinine Bisulfate Heptahydrate is produced and tested under a rigorous quality management system. Each batch is analyzed to ensure it meets stringent specifications for identity, purity, and composition. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from tests such as HPLC assay, identification by IR spectroscopy, and loss on drying. We can supply material compliant with various pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and weight.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Loss on Drying	20.0% - 24.0%
Specific Rotation	-220° to -235° (c = 2 in 0.1M HCl)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.