Description

Butanoic Acid, 4-Iodo-, 1,1-Dimethylethyl Ester is a specialized iodinated butanoate ester, a high-purity organic intermediate of significant interest in advanced synthetic chemistry. Its value lies in its unique molecular structure, which incorporates both a reactive iodine atom and a sterically hindered tert-butyl ester group, making it a versatile building block for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the iodine moiety facilitates important structural modifications.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings to form new carbon-carbon bonds.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and molecular probes for biochemical and diagnostic research applications.
• Organic Synthesis Building Block: Provides a protected carboxylic acid functionality and a handle for further derivatization in multi-step synthetic routes.

Basic Information

Product Name	Butanoic Acid, 4-Iodo-, 1,1-Dimethylethyl Ester
CAS No.	6182-78-1
Molecular Formula	C8H15IO2
Molecular Weight	270.11 g/mol
Synonyms	4-Iodobutanoic Acid tert-Butyl Ester; tert-Butyl 4-Iodobutanoate; Butanoic acid, 4-iodo-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-iodobutanoate; 4-Iodo-n-butyric Acid tert-Butyl Ester; tert-Butyl 4-iodobutyrate; Butanoic acid, 4-iodo-, tert-butyl ester; 6182-78-1
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 4-Iodo-, 1,1-Dimethylethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is between 2°C and 8°C for long-term stability, although the product is typically stable at controlled room temperature for shorter periods. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.