Description

Ethyl 4H-Chromene-2-Carboxylate is a versatile organic ester compound that serves as a key building block in advanced chemical synthesis. Its value lies in its chromene core, a privileged scaffold in medicinal chemistry known for imparting a wide range of biological activities. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients. Its defined structure and purity are critical for ensuring the reproducibility and efficacy of downstream products.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory, antimicrobial, and anticancer pathways.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the bioactivity of the chromene moiety.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for synthesizing specialized organic semiconductors and light-emitting materials.
• Dye and Pigment Chemistry: Acts as an intermediate for creating novel chromene-based dyes with specific optical properties.
• Flavor and Fragrance Industry: Potential use in the synthesis of complex aroma chemicals due to its ester functionality and heterocyclic structure.
• Academic and R&D: A valuable reagent for methodological studies in organic synthesis and for exploring new chemical spaces in combinatorial chemistry.

Basic Information

Product Name	Ethyl 4H-Chromene-2-Carboxylate
CAS No.	6179-32-4
Molecular Formula	C₁₂H₁₂O₃
Molecular Weight	204.22 g/mol
Synonyms	Ethyl 4H-1-Benzopyran-2-carboxylate; 2-Carbethoxy-4H-chromene; Ethyl 2H-Chromene-2-carboxylate; Ethyl Chromene-2-carboxylate; 4H-Chromene-2-carboxylic acid, ethyl ester; 2-Ethoxycarbonyl-4H-chromene; 4H-1-Benzopyran-2-carboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4H-Chromene-2-Carboxylate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.