Description

Cyclopropanecarboxylicacid, 2-(4-Methoxyphenyl)-, Ethyl Ester, (1R,2R)-Rel- CAS NO 6142-64-9 is a high-purity, chiral cyclopropane derivative characterized by its specific stereochemistry. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Serves as a crucial building block for constructing stereochemically defined molecular architectures in medicinal chemistry.
• Agrochemical Research: Used in the development of novel, high-efficacy pesticides and herbicides with specific chiral activity.
• Ligand and Catalyst Development: Employed in the research and preparation of chiral ligands for catalytic asymmetric transformations.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique optical or mechanical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	Cyclopropanecarboxylicacid, 2-(4-Methoxyphenyl)-, Ethyl Ester, (1R,2R)-Rel-
CAS No.	6142-64-9
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	(1R,2R)-rel-2-(4-Methoxyphenyl)cyclopropanecarboxylic Acid Ethyl Ester; Ethyl (1R,2R)-rel-2-(4-Methoxyphenyl)cyclopropanecarboxylate; Ethyl 2-(p-Methoxyphenyl)cyclopropanecarboxylate, (1R,2R)-rel-; trans-2-(4-Methoxyphenyl)cyclopropanecarboxylic Acid Ethyl Ester; Ethyl trans-2-(4-Methoxyphenyl)cyclopropanecarboxylate; 2-(4-Methoxyphenyl)cyclopropanecarboxylic Acid Ethyl Ester; (1R,2R)-2-(4-Methoxyphenyl)cyclopropanecarboxylic Acid Ethyl Ester (Relative Configuration)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to guarantee high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (for specified isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.