Description

Rel-Methyl (1S,3S)-3-Hydroxycyclohexane-1-Carboxylate is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable precursor for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially in therapeutic areas requiring stereochemical purity.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to introduce the (1S,3S) stereochemistry into target molecules.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways in laboratory-scale research.
• Agrochemical Synthesis: Potential intermediate in the development of chiral agrochemicals, where specific stereoisomers can exhibit enhanced biological activity.

Basic Information

Product Name	Rel-Methyl (1S,3S)-3-Hydroxycyclohexane-1-Carboxylate
CAS No.	6125-56-0
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Methyl (1S,3S)-3-Hydroxycyclohexanecarboxylate; (1S,3S)-3-Hydroxycyclohexanecarboxylic Acid Methyl Ester; rel-(1S,3S)-Methyl 3-Hydroxycyclohexanecarboxylate; (1S,3S)-Methyl 3-Hydroxycyclohexane-1-carboxylate; cis-3-Hydroxycyclohexanecarboxylic Acid Methyl Ester (relative stereochemistry); Cyclohexanecarboxylic acid, 3-hydroxy-, methyl ester, (1S,3S)-rel-
EINECS	Contact for details

Quality Control

Our Rel-Methyl (1S,3S)-3-Hydroxycyclohexane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (for (1S,3S) isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.