Description

α-Acetyllysine Methyl Ester is a key protected derivative of the essential amino acid L-lysine, specifically designed for advanced peptide synthesis and biochemical research. This compound is critical for researchers and manufacturers who require precise control over lysine residue reactivity, enabling the construction of complex peptides and protein analogs. It serves as a vital building block for pharmaceutical R&D, particularly in developing therapeutic peptides, prodrugs, and biochemical probes where selective deprotection is necessary.

Application

• Pharmaceutical Intermediate: A crucial building block in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in proteomics and enzyme studies to introduce acetylated lysine analogs, mimicking post-translational modifications.
• Prodrug Development: Serves as a precursor for prodrug formulations where controlled release of the active lysine moiety is required.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Chemical Biology Tool: Facilitates the study of protein-protein interactions and epigenetic markers involving acetyl-lysine.
• Cosmetic Peptide Synthesis: Used in the development of bioactive peptides for advanced skincare and cosmetic formulations.

Basic Information

Product Name	α-Acetyllysine Methyl Ester
CAS No.	6072-02-2
Molecular Formula	C9H18N2O3
Molecular Weight	202.25 g/mol
Synonyms	Nα-Acetyl-L-lysine methyl ester; N-Acetyl-L-lysine methyl ester; L-Lysine, N2-acetyl-, methyl ester; Methyl Nα-acetyl-L-lysinate; Ac-Lys-OMe; (S)-Methyl 2-acetamido-6-aminohexanoate; Nε-Acetyl-L-lysine methyl ester (common misnomer); N-Acetyllysine methyl ester
EINECS	Contact for details

Quality Control

Our α-Acetyllysine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.