Description

Estradiol 17-Acetate is a synthetic ester derivative of the primary female sex hormone, estradiol. This compound is a crucial pharmaceutical intermediate and reference standard in the development and quality control of steroidal medications. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and life sciences sectors for the synthesis of more complex hormone therapies and for analytical purposes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex steroidal drugs and hormone replacement therapies (HRT).
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of estradiol-based products via HPLC, GC, or MS.
• Biochemical Research: Employed in preclinical and clinical studies to investigate estrogen receptor binding, metabolic pathways, and endocrine system functions.
• Veterinary Medicine: Utilized in the formulation of hormonal treatments for animals.
• Cosmeceutical R&D: Investigated for potential applications in advanced dermatological and anti-aging formulations.

Basic Information

Product Name	Estradiol 17-Acetate
CAS No.	6045-67-6
Molecular Formula	C20H26O3
Molecular Weight	314.42 g/mol
Synonyms	Estradiol 17-Acetate; 17β-Estradiol 17-acetate; Estra-1,3,5(10)-triene-3,17β-diol 17-acetate; 3,17β-Dihydroxyestra-1,3,5(10)-trien-17-yl acetate; NSC 9895; 17β-O-Acetylestradiol; Estradiol acetate (17-)
EINECS	227-947-5

Quality Control

Our Estradiol 17-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results for parameters including assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.